baryawno lab


2017              2016            2013            2011            2008


The immune cell atlas of human neuroblastoma

Verhoeven BM*, Mei S*, Olsen TK, Gustafsson K, Valind A,  Lindström A, Gisselsson D, Fard SS, Hagerling C, Kharchenko PV, Kogner P, Johnsen JI, Baryawno N.


Cell Reports Medicine
Year: 2022


Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment

Kfoury N*, Baryawno N* Severe N*, Mei S*, Gustafsson K*, Hirz T*, Brouse T, Scadden EW, Igolkina AA, Kokkaliaris K, Choi BD, Barkas N, Randolph MA, Shin JH, Saylor PJ, Scadden DT, Sykes DB, Kharchenko PV, and as part of the Boston Bone Metastases Consortium.


Cancer Cell
Year: 2021
Volume: 39
Page: 1439-1548


A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia.

Baryawno N, Przybylski D, Kowalczyk MS, Kfoury Y, Severe N, Gustafsson UK, Kokkaliaris KD, Mercier F, Tabaka M, Hofree M, Dionne D, Papazian A, Lee D, Ashenberg O, Subramanian A, Vaishnav ED, Rozenblatt-Rosen O,  Regev A, Scadden DT.

Year: 2019
Volume: 177
Page: 1915-1932


Modulating Bone Marrow Hematopoietic Lineage Potential to Prevent Bone Metastasis in Breast Cancer.

Ubellacker JM, Baryawno N, Severe N, DeCristo MJ, Sceneay J, Hutchinson JN, Haider MT, Rhee CS, Qin Y, Gregory WM, Garrido-Castro AC, Holen I, Brown JE, Coleman RE, Scadden DT, McAllister SS.

Cancer Research
Year: 2018
Volume: 78
Page: 5300-5314


dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments.

Petukhov V, Guo J, Baryawno N, Severe N, Scadden DT, Samsonova MG, Kharchenko PV.

Genome Biology
Year: 2018
Volume: 19
Page: 78


Introduction to Single-Sell RNA Sequencing.

Ohlsen TK, Baryawno N.

Current Protocols
Year: 2018
Volume: 122
Page: e57


Bone marrow drives central nervous system regeneration after radiation injury.

Dietrich J, Baryawno N, Nayyar N, Valtis YK, Yang B1, Ly I, Besnard A, Severe N, Gustafsson KU, Andronesi OC, Batchelor TT, Sahay A, Scadden DT.

Journal Of Clinical Investigation
Year: 2017
Volume: 128
Page: 281-293


Hematopoiesis: Reconciling Historic Controversies about the Niche.

Baryawno N, Severe N, Scadden DT.

Cell Stem Cell
Year: 2017
Volume: 20
Page: 590-592

Graphical Abstract Sized

Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell.

Hoggatt J, Singh P, Tate TA, Chou BK, Datari SR, Fukuda S, Liu L, Kharchenko PV, Schajnovitz A, Baryawno N, Mercier FE, Boyer J, Gardner J, Morrow DM, Scadden DT, Pelus LM.

Year: 2017
Volume: 172
Page: 191-204


Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils.

Engblom C, Pfirschke C, Zilionis R, Da Silva Martins J, Bos SA, Courties G, Rickelt S, Severe N, Baryawno N, Faget J, Savova V, Zemmour D, Kline J, Siwicki M, Garris C, Pucci F, Liao HW, Lin YJ, Newton A, Yaghi OK, Iwamoto Y, Tricot B, Wojtkiewicz GR, Nahrendorf M, Cortez-Retamozo V, Meylan E, Hynes RO, Demay M, Klein A, Bredella MA, Scadden DT, Weissleder R, Pittet MJ.

Year: 2017
Volume: 358
Issue: 6367


Amino acid-insensitive mTORC1 regulation enables nutritional stress resilience in hematopoietic stem cells.

Kalaitzidis D, Lee D, Efeyan A, Kfoury Y, Nayyar N, Sykes DB, Mercier FE, Papazian A, Baryawno N, Victora GD, Neuberg D, Sabatini DM, Scadden DT.

J Clin Invest
Year: 2017
Volume: 127
Page: 1405-1413


Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators.

Silberstein L, Goncalves KA, Kharchenko PV, Turcotte R, Kfoury Y, Mercier F, Baryawno N, Severe N, Bachand J, Spencer JA, Papazian A, Lee D, Chitteti BR, Srour EF, Hoggatt J, Tate T, Lo Celso C, Ono N, Nutt S, Heino J, Sipilä K, Shioda T, Osawa M, Lin CP, Hu GF, Scadden DT.

Cell Stem Cell
Year: 2016
Volume: 19
Page: 530-543


Epigenetic Memory Underlies Cell Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells

Yu VWC , Yusuf RZ, OkiT, Wu J, Saez B, Wang X, Cook C, Baryawno N, Ziller MJ, Lee E, Gu H, Meissner A, Lin CP, Kharchenko PV, Scadden DT.

Year: 2016
Volume: 167
Pages: 1310-1322


Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance

Wickström M, Dyberg C, Milosevic J, Christer E, Calero R, Sveinbjörnsson B, Sandeé E, Darabi A, Siesjö P, Kool M, Kogner P, Baryawno N* & Johnsen J*.

Nature Commun
Year: 2015
Volume: 25
Article Number: 8904

Baryawno Lab Publications

Frequent detection of human cytomegalovirus in neuroblastoma: A novel therapeutic target?

Wolmer-Solberg N*, Baryawno N*, Rahbar A, Fuchs D, Odeberg J, Taher C, Wilhelmi V, Milosevic J, Mohammad AA, Martinsson T, Sveinbjörnsson B, Johnsen JI, Kogner P, Söderberg-Nauclér C.

International Journal of Cancer
Year: 2013
Volume: 133 (10)
Article Number:  2351-61


Detection of human cytomegalovirus in medulloblastomas reveals a novel therapeutic target

Baryawno N, Rahbar A, Wolmer-Solberg N, Taher C, Odeberg J, Darabi A, Khan Z, Sveinbjörnsson B, Fuskevåg OM, Segerström L, Nordenskjöld M, Siesjö P, Kogner P, Johnsen JI and Söderberg-Nauclér C.

Journal of Clinical Investigation
Year: 2011
Volume: 121
Article Number: 4043-55


Small molecule inhibitors of PI3K/AKT signaling inhibit Wnt/β-catenin pathway crosstalk and suppress medulloblastoma growth.

Baryawno N, Sveinbjörnsson B, Eksborg S, Chen CS, Kogner P, Johnsen JI.

Cancer Research
Year: 2011
Volume: 70
Pages: 266-76


Tumour growth promoting cyclooxygenase-2 prostaglandin E2 pathway provides medulloblastoma therapeutic targets

Baryawno N, Sveinbjörnsson B, Eksborg S, Orrego A, Segerström L, Öqvist CO, Holm S, Gustavsson B, Kågedal B, Kogner P, Johnsen JI.

Year: 2008
Volume: 10
Pages: 661-74